Human CellExp™ Cystatin C, Human Recombinant

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SKU:
4878-50
$719.07
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Description

Human CellExp™ Cystatin C, Human Recombinant is available at Gentaur for Next week delivery.

A biomarker of kidney function

Biomolecule/Target:

Alternates names: Cystatin-3, Gamma-trace neuroendocrine basic polypeptide, Post-gamma-globulin

Synonyms: Human Recombinant Cystatin C

Background Information: Xeno-free Cystatin C HuXp (Cys-C) is expressed in human 293 cells as a monomer with an apparent molecular mass of 12 to 13 kDa. Native Cys-C in human urine is found in two different forms: one with pI 9.2 and the other with pI 7.8 by elimination of small basic peptides or amino acids from the N-terminal end of protein. Cystatin C has been studied for its role in predicting new onset or deteriorating cardiovascular disease. This cytokine is produced in a serum-free, chemically defined media.

Reconstitution Instructions: Reconstitute in sterile PBS.

NCBI Gene Symbol: CST4

Gene ID: 1472

NCBI Accession: P01036

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
Human 293 cells
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The inhibitory function of Cystatin C on papin’s protease activity was measured by a colorimetric assay using L-BAPA as substrate. IC50 value was measured at 5 to 20 µg/mL (0.3 to 1.5 µM) with a range of 1.56 µg/mL to 50 µg/mL Cystatin C in presence
Results:
Typically 0.3 to 1.5 µM IC50.
Molecular Weight:
12-13 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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