Human CellExp™ CD71 / TFRC / TFR, human recombinant

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SKU:
7279-50
£135.37
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Description

Human CellExp™ CD71 / TFRC / TFR, human recombinant is available at Gentaur for Next week delivery.

A protein required for iron delivery from transferrin to cells

Biomolecule/Target: CD71 /TFRC /TFR

Alternates names: CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90

Synonyms: CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90

Background Information: CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukemia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

NCBI Gene Symbol: TFRC

Gene ID: 7037

NCBI Accession: P02786

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
HEK293 cells
Purity by SDS-PAGE:
≥92%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
<1 EU/μg by LAL method
Activity (Specifications/test method):
N/A
Biological activity:
Measured by its binding ability in a functional ELISA. Immobilized rhCD71/TFR at 10 μg/ml (100 μl/well) can bind human Transferrin. The EC50 of human Transferrin is 6.4 ng/ml.
Results:
Measured by its binding ability in a functional ELISA. Immobilized rhCD71/TFR at 10 μg/ml (100 μl/well) can bind human Transferrin. The EC50 of human Transferrin is 6.4 ng/ml.
Molecular Weight:
This protein is fused with 6×His tag at the N-terminus, has a calculated MW of 76 kDa. The predicted N-terminus is Cys 89. DTT-reduced Protein migrates as 80-85 kDa due to glycosylation.
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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