BioVision Products
Human CellExp™ CD71 / TFRC / TFR, human recombinant
- SKU:
- 7279-50
Description
Human CellExp™ CD71 / TFRC / TFR, human recombinant is available at Gentaur for Next week delivery.
A protein required for iron delivery from transferrin to cells
Biomolecule/Target: CD71 /TFRC /TFR
Alternates names: CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90
Synonyms: CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90
Background Information: CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukemia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
NCBI Gene Symbol: TFRC
Gene ID: 7037
NCBI Accession: P02786
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
≥92% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
<1 EU/μg by LAL method |
Activity (Specifications/test method): |
N/A |
Biological activity: |
Measured by its binding ability in a functional ELISA. Immobilized rhCD71/TFR at 10 μg/ml (100 μl/well) can bind human Transferrin. The EC50 of human Transferrin is 6.4 ng/ml. |
Results: |
Measured by its binding ability in a functional ELISA. Immobilized rhCD71/TFR at 10 μg/ml (100 μl/well) can bind human Transferrin. The EC50 of human Transferrin is 6.4 ng/ml. |
Molecular Weight: |
This protein is fused with 6×His tag at the N-terminus, has a calculated MW of 76 kDa. The predicted N-terminus is Cys 89. DTT-reduced Protein migrates as 80-85 kDa due to glycosylation. |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |