BioVision Proteins
Human CellExp™ CD58 / LFA-3, Fc Tag, human recombinant
- SKU:
- P1150-50
Description
Human CellExp™ CD58 / LFA-3, Fc Tag, human recombinant is available at Gentaur for Next week delivery.
Ligand of T-lymphocyte CD2 glycoprotein
Biomolecule/Target: CD58
Alternates names: CD58, LFA3, Ag3
Synonyms: CD58, LFA3, Ag3
Background Information: CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
NCBI Gene Symbol: CD58
Gene ID: 965
NCBI Accession: P19256
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
HEK 293 cells |
Purity by SDS-PAGE: |
> 95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 1.0 EU per/μg |
Activity (Specifications/test method): |
Measured by its binding ability in a functional ELISA. |
Biological activity: |
Immobilized Human CD2, His Tag at 2 μg/mL (100 μL/well) can bind Human CD58, Fc Tag with a linear range of 10-156 ng/mL |
Results: |
N/A |
Molecular Weight: |
48.1 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |