Human CellExp™ CD3 epsilon (His-tag) & CD3 delta Heterodimer

Human CellExp™ CD3 epsilon (His-tag) & CD3 delta Heterodimer is available at Gentaur for Next week delivery.

CD3 epsilon (his-tag) and CD3 delta heterodimer important in coupling antigen recognition

Biomolecule/Target:

Alternates names: Human CellExp™ CD3 delta/epsilon,CD3E & CD3D,Human CellExp™ CD3 epsilon (His-tag) - CD3 delta Heterodimer,Human CellExp™ CD3 epsilon-CD3 delta Heterodimer,CD3 d/e,CD3 delta/epsilon,Human CellExp™ CD3 epsilon (His-tag) CD3 delta Heterodimer,CD3 delta & CD3 epsilon,CD3 epsilon (His-tag) - CD3 delta Heterodimer

Synonyms: Human CellExp™ CD3 delta/epsilon,CD3E & CD3D,Human CellExp™ CD3 epsilon (His-tag) - CD3 delta Heterodimer,Human CellExp™ CD3 epsilon-CD3 delta Heterodimer,CD3 d/e,CD3 delta/epsilon,Human CellExp™ CD3 epsilon (His-tag) CD3 delta Heterodimer,CD3 delta & CD3 epsilon,CD3 epsilon (His-tag) - CD3 delta Heterodimer

Background Information: T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3E, CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta, and gamma/delta heterodimers, form the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Since CD3 is required for T-Cell activation, drugs and therapeutics targeting CD3 are being researched for diseases like Type 1 diabetes and other autoimmune diseases. For example, Muromonab-CD3, a monoclonal antibody targeting the CD3 receptor, is an immunosuppressant drug to reduce acute rejection in patients with organ transplants.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS (pH 7.4). Reconstitute in sterile PBS (pH 7.4).

NCBI Gene Symbol: CD3E, CD3D

Gene ID: 916, 915

NCBI Accession: P07766, P04234