BioVision Proteins
Human CellExp™ CD3 epsilon & CD3 delta Heterodimer
- SKU:
- P1183-10
Description
Human CellExp™ CD3 epsilon & CD3 delta Heterodimer is available at Gentaur for Next week delivery.
T cell receptor plays an important role in coupling antigen recognition
Biomolecule/Target: CD3E, CD3D
Alternates names: CD3E & CD3D, CD3 delta & CD3 epsilon, CD3 delta / epsilon
Synonyms: CD3E & CD3D, CD3 delta & CD3 epsilon, CD3 delta / epsilon
Background Information: T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
NCBI Gene Symbol: CD3E, CD3D
Gene ID: 916, 915
NCBI Accession: P07766, P04234
Additional Information
Size: |
10 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
Expi293 cells |
Purity by SDS-PAGE: |
>95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 1.0 EU per/μg |
Activity (Specifications/test method): |
Measured by its binding ability in a functional ELISA. |
Biological activity: |
Human CD3 epsilon & CD3 delta Heterodimer Protein was immobilized at 0.5 µg/ml (100 µl/well). Dose response curve using Anti-hCD3E/CD3D Ab foralumab gave an EC₅₀ of 21.69 ng/ml by ELISA. Human CD3 epsilon & CD3 delta Heterodimer Protein was Immobiliz |
Results: |
N/A |
Molecular Weight: |
16.7 kDa and 13.5 kDa |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |