Description
Galectin-2, mouse recombinant is available at Gentaur for Next week delivery.
A protein involved tumor progression, pre-mRNA splicing and apoptosis.
Biomolecule/Target: Lgals2
Alternates names: Lgals2, 2200008F12Rik, AI324148
Synonyms: Lgals2, 2200008F12Rik, AI324147, Gal-2
Background Information: Galectin 2, also known as Lgals2, belongs to the galectins family. Galectins are a family of soluble beta-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Lgals2 is a monomeric or homodimeric prototype galectin that is expressed in hepatoma, stomach epithelial cells and in colorectal and neural tumors. It induces apoptosis in activated T cells and binds to the cytokine lymphotoxin-a (LTA) with possible implications in risk of myocardial infarction. Human and mouse Lgals2 share approximately 65% amino acid sequence similarity. Recombinant Mouse Lgals2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Reconstitution Instructions: N/A
NCBI Gene Symbol: Lgals2
Gene ID: 107753
NCBI Accession: Q9CQW5
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Mouse |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
> 95% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
The ED50 for this effect is ≤20 ug/ml. Measured by its ability to agglutinate human red blood cells. |
Results: |
ED50 is ≤20 ug/ml. |
Molecular Weight: |
17.3 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |