Galectin-3, mouse recombinant

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SKU:
P1045-50
€185
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Description

Galectin-3, mouse recombinant is available at Gentaur for Next week delivery.

A protein involved in cell growth and differentiation, cell cycle, and apoptosis.

Biomolecule/Target: Lgals3

Alternates names: CBP35, GAL3, GALBP, GALIG, LGALS2, MAC2.

Synonyms: Lectin, galactose binding, soluble 3, CBP35, GAL3, GALBP, GALIG, LGALS2, MAC2

Background Information: LGALS3, also known as galectin 3, is a member of the family of animal lectins, which selectively binds betagalactosidemresidues. This protein is secreted from cells by ectocytosis, which is independent of the classical secretory pathway through the endoplasmic reticulum/Golgi network. LGALS3 has been associated with the inhibition of apoptosis and the progression of cancer. It is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. Recombinant mouse LGALS3 protein, used to Histag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Reconstitution Instructions: N/A

NCBI Gene Symbol: Lgals3

Gene ID: 16854

NCBI Accession: Q8C253

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Mouse
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
> 95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
Measured by its ability to agglutinate human red blood cells
Results:
ED50 is ≤25 ug/ml.
Molecular Weight:
29.8 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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