Galectin-3, human recombinant

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SKU:
4684-50
€185
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Description

Galectin-3, human recombinant is available at Gentaur for Next week delivery.

A protein involved in cell growth and differentiation, cell cycle, and apoptosis.

Biomolecule/Target:

Alternates names: IgE-binding protein, MAC2, L-29, CPB-35, 35 kDa lectin, Carbohydrate-binding protein 35, Galactose-specific lectin 3, Galactoside-binding protein, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen

Synonyms: IgE-binding protein, MAC2, L-29, CPB-35

Background Information: Lectins are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galactin-3 regulates a number of biological processes, including embryogenesis, inflammatory responses, cell progression and metastasis. Galectin-3 can function intraCellularly in controlling cell cycle and preventing T-cell apoptosis, and also extraCellularly, in activating various cells, including monocytes/macrophages, mast cells, neutrophils, and lymphocytes. Recombinant Galectin-3 is a globular 26.0 kDa protein containing 250 amino acid residues, but no disulfide bonds.

Reconstitution Instructions: Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

NCBI Gene Symbol: LEG3

Gene ID: 3958

NCBI Accession: P17931

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 µg/ml with a peak response obtained at 250 µg/ml.
Results:
250 µg/ml
Molecular Weight:
26.0 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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