FGF-basic 147, human recombinant

(No reviews yet) Write a Review
SKU:
4036-50
€185
Frequently bought together:

Description

FGF-basic 147, human recombinant is available at Gentaur for Next week delivery.

A growth factor involved in angiogenesis, wound healing and embryonic development

Biomolecule/Target: FGF-basic 147

Alternates names: FGF2, HBGF-2, Prostatropin, Basic fibroblast growth factor, Heparin-binding growth factor 2

Synonyms: FGFB

Background Information: Fibroblast Growth Factors, FGFs, are a 22 member family of proteins known to be involved in angiogenesis, wound healing and embryonic development. As a family, they bind to heparin and signal through four receptor tyrosine kinases called, FGFR1, 2, 3 and 4. Although the mechanism remains unclear, FGF-basic 147 (variant of FGF basic 154) is a critical component in keeping embryonic stem cells undifferentiated in cell culture systems. Recombinant human FGF-b 147 (FGF-2) is a non-glycosylated protein, containing 147 amino acids, and having a molecular mass of 16.5 kDa.

Reconstitution Instructions: Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions.

NCBI Gene Symbol: FGF2

Gene ID: 2247

NCBI Accession: P09038

View AllClose

Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥97%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
<0.01 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
EC50 is typically 0.67-1.45 ng/ml. The activity was determined by the dose-dependent stimulation of mouse BALB/c 3T3 cells.
Results:
0.67-1.45 ng/ml
Molecular Weight:
16.5 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
View AllClose

0 Reviews

View AllClose