FGF-2/FGF-basic, human recombinant

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SKU:
4037-50
€185
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Description

FGF-2/FGF-basic, human recombinant is available at Gentaur for Next week delivery.

Recombinant FGF2 from E.Coli, animal origin free, ≥95% pure, biologically active, cell culture tested. A growth factor involved in angiogenesis, wound healing and embryonic development.

Biomolecule/Target: FGF-2

Alternates names: FGF2, HBGF-2, Prostatropin, Basic fibroblast growth factor, Heparin-binding growth factor 2

Synonyms: Prostatropin, HBGH-2, HBGF-2, FGF-2, FGF-b, Fibroblast Growth Factor

Background Information: FGF-2 (FGF2, FGF 2, FGF-basic, basic FGF, bFGF) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-2 protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different FGF-2 isoforms have been described. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.

Reconstitution Instructions: Reconstitute human FGF-2 in 5 mM Tris, pH 7.6 to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers

NCBI Gene Symbol: FGF2

Gene ID: 2247

NCBI Accession: NM_002006

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Additional Information

Size:
50 μg
Adwords:
Yes
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
≥95%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The ED₅₀ of human FGF-2 is determined by the dose-dependent proliferation of mouse BALB/c 3T3 cells and is typically less than 3 ng/ml.
Results:
<0.5 ng/ml
Molecular Weight:
Human FGF-2 is a 17.2 kDa recombinant protein
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Recombinant FGF-2 is available as a lyophilized powder
Handling:
Centrifuge the vial prior to opening.
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