CD5, human recombinant

CD5, human recombinant is available at Gentaur for Next week delivery.

A good immunohistochemical marker for T-cells

Biomolecule/Target: CD5

Alternates names: T-cell surface glycoprotein CD5, LEU1, T1

Synonyms: T-cell surface glycoprotein CD5, LEU1, T1

Background Information: CD5 is a good immunohistochemical marker for T-cells, although not as sensitive as CD3. About 76% of T-cell neoplasms are reported to express CD5, and it is also found in chronic lymphocytic leukemia, hairy cell leukemia, and mantle cell lymphoma cells. It is commonly lost in cutaneous T-cell lymphoma, and its absence can be used as an indicator of malignancy in this condition. The absence of CD5 in T cell acute lymphoblastic leukemia, while relatively rare, is associated with a poor prognosis. Recombinant human CD5 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Reconstitution Instructions: N/A

NCBI Gene Symbol: CD5

Gene ID: 921

NCBI Accession: P06127