CD5, human recombinant

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SKU:
7315-50
€185
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Description

CD5, human recombinant is available at Gentaur for Next week delivery.

A good immunohistochemical marker for T-cells

Biomolecule/Target: CD5

Alternates names: T-cell surface glycoprotein CD5, LEU1, T1

Synonyms: T-cell surface glycoprotein CD5, LEU1, T1

Background Information: CD5 is a good immunohistochemical marker for T-cells, although not as sensitive as CD3. About 76% of T-cell neoplasms are reported to express CD5, and it is also found in chronic lymphocytic leukemia, hairy cell leukemia, and mantle cell lymphoma cells. It is commonly lost in cutaneous T-cell lymphoma, and its absence can be used as an indicator of malignancy in this condition. The absence of CD5 in T cell acute lymphoblastic leukemia, while relatively rare, is associated with a poor prognosis. Recombinant human CD5 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Reconstitution Instructions: N/A

NCBI Gene Symbol: CD5

Gene ID: 921

NCBI Accession: P06127

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥80%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
< 1.0 EU per 1 microgram of protein
Activity (Specifications/test method):
N/A
Biological activity:
N/A
Results:
N/A
Molecular Weight:
41.0 kDa (371 aa, 25-372 aa + His tag), confirmed by MALDI-TOF.
Storage Temperature:
-80°C
Shelf Life:
12 months
Concentration:
1 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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