Caspase-9 Proform, human recombinant

Caspase-9 Proform, human recombinant is available at Gentaur for Next week delivery.

An aspartic acid protease involved in apoptosis

Biomolecule/Target: Caspase-9

Alternates names: Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, ICE-like apoptotic protease 6, ICE-LAP6, LEHDase

Synonyms: Caspase-9 Proform

Background Information: Caspase-9 is a member of the caspase family of cysteine proteases. Caspase-9 exists in cells as an inactive proenzyme. Proteolytic processing of this inactive proenzyme generates the large and small subunits which, when assembled as a tetramer (a pair of heterodimers), form the active caspase. Cascades of caspase activation have been shown to be the key signal-transducing events in apoptosis. Caspase-9 is considered to be an upstream enzyme that initiates caspase cascade leading to apoptosis. The recombinant Procaspase-9 is produced by expression of a human cDNA in E. coli and further purified by multiple chromatographic steps.

Reconstitution Instructions: N/A

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