Caspase-9, human recombinant

Caspase-9, human recombinant is available at Gentaur for Next week delivery.

An aspartic acid protease involved in apoptosis

Biomolecule/Target: Caspase-9

Alternates names: Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, ICE-like apoptotic protease 6, ICE-LAP6, LEHDase

Synonyms: Caspase-9

Background Information: Caspase-9 is a member of the caspase-family of cysteine proteases. Similar to other caspases, caspase-9 also exists in cells as an inactive proenzyme. During the initiation of apoptosis procaspase-9 is processed at aspartate residues to form active caspase-9. As one of the initiator caspases, active caspase-9 functions to trigger activation of downstream effector caspases, leading to disassembly of cell structures. The recombinant active human caspase-9 was expressed in E. coli. The active caspase-9 is routinely tested at BioVision for its ability to enzymatically cleave these two substrates Ac-LEHD-pNA (Cat. #1076-200) or Ac-LEHD-AFC (1075-200).

Reconstitution Instructions: Reconstitute to 1 unit per μl in PBS containing 15% glycerol.

NCBI Gene Symbol: CASP9

Gene ID: 842

NCBI Accession: P55211