Caspase-7, human recombinant

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SKU:
1087-25
$183
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Description

Caspase-7, human recombinant is available at Gentaur for Next week delivery.

A cysteine protease involved in apoptosis

Biomolecule/Target: Caspase-7

Alternates names: Caspase-7, CASP-7, Apoptotic protease Mch-3, CMH-1, ICE-like apoptotic protease 3

Synonyms: Caspase-7

Background Information: Caspase-7 (also know as Mch3, ICE-LAP3, CMH-1) is a member of the caspase-family of cysteine proteases. Similar to other caspases, caspase-7 also exists in cells as an inactive proenzyme. During apoptosis procaspase-7 is processed at aspartate residues by self-proteolysis and/or cleavage by another caspase. The processed active form of caspase-7 consists of large and small subunits which associate to form the active enzyme. Active caspase-7 has been shown involving in the proteolysis of PARP (poly ADP-ribose polymerase), an enzyme that is involved in DNA repair and genomic maintenance. The recombinant active human caspase-7 was expressed in E. coli. The active caspase-7 is routinely tested at BioVision for its ability to enzymatically cleave these two substrates Ac-DEVD-pNA (Cat. #1008-200) or Ac-DEVD-AFC (1007-200).

Reconstitution Instructions: Reconstitute to 1 unit per µl in PBS containing 15% glycerol.

NCBI Gene Symbol: CASP7

Gene ID: 840

NCBI Accession: P55210

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Additional Information

Size:
25units
Adwords:
Yes
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli.
Purity by SDS-PAGE:
≥90%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
N/A
Activity (Specifications/test method):
> 25000 units/mg
Biological activity:
N/A
Results:
N/A
Molecular Weight:
N/A
Storage Temperature:
-70°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized powder
Handling:
Centrifuge the vial prior to opening.
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