Caspase-6, human recombinant

(No reviews yet) Write a Review
SKU:
1086-25
$719.07
Frequently bought together:

Description

Caspase-6, human recombinant is available at Gentaur for Next week delivery.

A cysteine-aspartic acid protease involved in apoptosis

Biomolecule/Target: Caspase-6

Alternates names: Caspase-6, CASP-6, Apoptotic protease Mch-2

Synonyms: Caspase-6

Background Information: Caspase-6 (also know as Mch2) is a member of the caspase-family of cysteine proteases. Similar to other caspases, caspase-6 also exists in cells as an inactive proenzyme. During apoptosis procaspase-6 is processed at aspartate residues by self-proteolysis and/or cleavage by another caspase. The processed active form of caspase-6 consists of large (18 kDa) and small (11 kDa) subunits which associate to form the active enzyme. Active caspase-6 has been shown involving in the proteolysis of PARP (poly ADP-ribose polymerase), an enzyme that is involved in DNA repair and henomic maintenance. The recombinant active human caspase-6 was expressed in E. coli. The active caspase-6 is routinely tested at BioVision for its ability to enzymatically cleave these two substrates Ac-VEID-pNA (Cat. #1070-200) or Ac-VEID-AFC (1069-200).

Reconstitution Instructions: Reconstitute to 1 unit per µl in PBS containing 15% glycerol.

NCBI Gene Symbol: CASP6

Gene ID: 839

NCBI Accession: P55212

View AllClose

Additional Information

Size:
25 units
Adwords:
Yes
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli.
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
N/A
Activity (Specifications/test method):
> 13000 units/mg
Biological activity:
N/A
Results:
N/A
Molecular Weight:
large (18 kDa) and small (11 kDa)
Storage Temperature:
-70°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized powder
Handling:
Centrifuge the vial prior to opening.
View AllClose

0 Reviews

View AllClose