Angiostatin K1-3, human recombinant

Angiostatin K1-3, human recombinant is available at Gentaur for Next week delivery.

A specific inhibitor of endothelial cell growth and angiogenesis

Biomolecule/Target:

Alternates names: Angiostatin K1-4, Angiostatin Kringles 1-4, plasminogen

Synonyms: Angiostatin K1-3, Angiostatin Kringles 1-3

Background Information: Ang K1-3 is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. A specific inhibitor of endothelial cell growth and angiogenesis. Displays increased inhibitory activity (ED₅₀ =70 nM) relative to kringles 1-4 (ED₅₀ = 135 nM). Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth.

Reconstitution Instructions: Reconstitute in sterile distilled H₂O or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.

NCBI Gene Symbol:

Gene ID:

NCBI Accession: P00747