BioVision Proteins
Active Recombinant Human CAXII Protein
- SKU:
- P1704-50
Description
Active Recombinant Human CAXII Protein is available at Gentaur for Next week delivery.
Overexpressed in renal carcinomas
Biomolecule/Target:
Alternates names:
Synonyms: Carbonic anhydrase 12 isoform 1, CAXII, HsT18816, CA12, FLJ20151, Carbonate dehydratase XII, carbonic anhydrase XII, CA-XII, Tumor antigen HOM-RCC-3.1.3
Background Information: CA12, also known as Carbonic anhydrase 12, is an enzyme that in humans is encoded by the CA12 gene. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas.
Reconstitution Instructions:
NCBI Gene Symbol:
Gene ID: 771
NCBI Accession: O43570
Additional Information
Size: |
50 μg |
Adwords: |
False |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
False |
Source: |
Baculovirus |
Purity by SDS-PAGE: |
≥ 90% by SDS-PAGE |
Endotoxin Level: |
< 1 EU per 1 µg of protein as determined by LAL method |
Activity (Specifications/test method): |
Specific activity is > 300 pmol/min/μg, and is defined as the amount of enzyme that hydrolyzes 1.0 pmole of 4-nitrophenyl acetate to 4-nitrophenol per minute at pH 7.5 at 37 °C. |
Molecular Weight: |
31.94 kDa |
Storage Temperature: |
-20ºC |
Shelf Life: |
12 months |
Concentration: |
0.5 mg/mL |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |