Description
Active AHCY, human recombinant is available at Gentaur for Next week delivery.
Catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy).
Biomolecule/Target: AHCY/SAHH
Alternates names: SAHH, AdoHcyase, S-adenosyl-L-homocysteine hydrolase, Adenosyl Homocysteinase
Synonyms: SAHH, AdoHcyase, S-adenosyl-L-homocysteine hydrolase, Adenosyl Homocysteinase
Background Information: AHCY (EC 3.3.1.1) is an enzyme that catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). AHCY controls the intracellular S-adenosylhomocysteine (SAH) concentration that is crucial for transmethylation reactions. AHCY deficiency causes hypermethioninemia. The recombinant human AHCY produced in E.Coli is a single, non-glycosylated polypeptide chain and is purified by proprietary chromatographic techniques.
Reconstitution Instructions: N/A
NCBI Gene Symbol: AHCY
Gene ID: 191
NCBI Accession: P23526
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥90% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
BioVision’s Active AHCY has been tested for its activity using Adenosyl Homocysteinase (AHCY) Activity Fluorometric Assay Kit (K807-100). It has a specific activity of >350 mU/mg. |
Results: |
BioVision’s Active AHCY has been tested for its activity using Adenosyl Homocysteinase (AHCY) Activity Fluorometric Assay Kit (K807-100). It has a specific activity of >350 mU/mg. |
Molecular Weight: |
52.1 kDa (1-432 aa + N-terminal polyhistidine tag). In the native form the protein exists in the tetrameric form and this form is required for activity. |
Storage Temperature: |
-80°C |
Shelf Life: |
6 months |
Concentration: |
5 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |