Description
5-Lipoxygenase, Active, Human Recombinant is available at Gentaur for Next week delivery.
Non-heme iron-containing dioxygenases
Biomolecule/Target: 5-Lipoxygenase
Alternates names: ALOX5, 5-LOX, Arachidonate 5-lipoxygenase
Synonyms: ALOX5, 5-LOX, Arachidonate 5-lipoxygenase
Background Information: Lipoxygenases are non-heme iron-containing dioxygenases. These enzymes convert unsaturated fatty acids to epoxides, such as leukotrienes from arachidonic acid. They play an important role in cell proliferation, differentiation and inflammation; and have been implicated in inflammation and hyper proliferation mediated diseases like asthma, rheumatoid arthritis and cancer.
Reconstitution Instructions:
NCBI Gene Symbol: ALOX5
Gene ID: 240
NCBI Accession: P09917
Additional Information
Size: |
200 µU |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
VRAI |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Activity (Specifications/test method): |
≥ 300 µU/mg. The enzyme’s activity was assayed using BioVision’s Lipoxygenase Activity Assay Kit (Catalog Number: K978). |
Results: |
≥ 300 µU/mg |
Molecular Weight: |
68.3 kDa (1-579 aa + N-terminal His Tag) |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |