5-Lipoxygenase, Active, Human Recombinant

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SKU:
P1373-200
€185
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Description

5-Lipoxygenase, Active, Human Recombinant is available at Gentaur for Next week delivery.

Non-heme iron-containing dioxygenases

Biomolecule/Target: 5-Lipoxygenase

Alternates names: ALOX5, 5-LOX, Arachidonate 5-lipoxygenase

Synonyms: ALOX5, 5-LOX, Arachidonate 5-lipoxygenase

Background Information: Lipoxygenases are non-heme iron-containing dioxygenases. These enzymes convert unsaturated fatty acids to epoxides, such as leukotrienes from arachidonic acid. They play an important role in cell proliferation, differentiation and inflammation; and have been implicated in inflammation and hyper proliferation mediated diseases like asthma, rheumatoid arthritis and cancer.

Reconstitution Instructions:

NCBI Gene Symbol: ALOX5

Gene ID: 240

NCBI Accession: P09917

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Additional Information

Size:
200 µU
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
VRAI
Source:
E. coli
Purity by SDS-PAGE:
≥95%
Assay:
SDS-PAGE
Activity (Specifications/test method):
≥ 300 µU/mg. The enzyme’s activity was assayed using BioVision’s Lipoxygenase Activity Assay Kit (Catalog Number: K978).
Results:
≥ 300 µU/mg
Molecular Weight:
68.3 kDa (1-579 aa + N-terminal His Tag)
Storage Temperature:
-20°C
Shelf Life:
12 months
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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