Procathepsin B Antibody

Procathepsin B Antibodyis available at Gentaur for Next week Delivery.

Description: Cathepsin B is a normal lysosomal cysteine proteinase that is expressed in all cells. It is synthesized as an inactive 43 kDa pro-enzyme which, by removal of a 62 amino acid propeptide, is activated to the single-chain form of 31 kDa or the two-chain form (25 and 5 kDa subunits). Matured cathepsin B is normally localized in the lysosomes where it functions in protein turnover. Cathepsin B is also shown capable of degrading extracellular matrix proteins. Elevated levels of cathepsin B correlate with malignancy suggesting that this enzyme may be a useful prognostic marker for several types of human cancers.

Immunogen Sequence:Human Recombinant Procathepsin B, Cat # 7579

Target Alternative Name:CTSB, CPSB

Species Reactivities:Human, mouse, rat

Tag Line:Polyclonal Antibody to detect Procathepsin B in human, mouse and rat samples

Formulation:30 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.

Purification: Affinity Purified Antibody

Application:Western blot

Positive Control:Western Blot: Jurkat cell lysate, 3T3 cell lysate, rat kidney lysate, recombinant protein

Application And Usages:Western blot: 1-4 µg

Handling:The antibody solution should be gently mixed before use.