Antibodies Signaling Pathways

Anti-Phospho-AKT1 (Y315) / AKT2 (Y316) / AKT3 (Y312) Polyclonal Antibodyis available at Gentaur for Next week Delivery. Description: The human AKT serine-threonine kinase family consists of three members (AKT1, AKT2, and AKT3) that are phosphorylated by...

Anti-RanBP9 Polyclonal Antibody is available at Gentaur for Next week Delivery. Description: The RAN binding protein 9 (RanBP9) is a protein that interacts with Ran, a member of the RAS superfamily of GTP binding proteins that is essential for the...

Anti-LGR4, Humanized Antibodyis available at Gentaur for Next week Delivery. Description: LGR4 is a G-protein coupled receptor that binds R-spondins and activates the Wnt signaling pathway, which is necessary for the proper development of many organs in...

Anti-FGF23 Antibody (Clone# FGF23/4162)is available at Gentaur for Next week Delivery. Description: This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved...

Anti-USP7 Antibodyis available at Gentaur for Next week Delivery. Description: The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor...

Anti-HDAC1 (KO Validated) Antibodyis available at Gentaur for Next week Delivery. Description: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein...

Anti-GDF-15 Antibodyis available at Gentaur for Next week Delivery. Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading...

Phospho SMAD3 (Ser425) Antibodyis available at Gentaur for Next week Delivery. Description: The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against...

Phospho ELK1 (Thr417) Antibodyis available at Gentaur for Next week Delivery. Description: This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary...

Phospho HDAC5 (Ser498) Antibodyis available at Gentaur for Next week Delivery. Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome...

Phospho SMAD2 (Ser465) Antibodyis available at Gentaur for Next week Delivery. Description: Smads are a group of intracellular proteins that act as signal transducers for the members of TGF-beta superfamily. Based on their roles, Smads are categorized in...

Phospho eNOS (Ser1177) Antibodyis available at Gentaur for Next week Delivery. Description: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral...

Phospho ER-alpha (Ser167) Antibodyis available at Gentaur for Next week Delivery. Description: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and...

Phospho EEF2K (Ser366) Antibodyis available at Gentaur for Next week Delivery. Description: This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division...

Phospho Histone H3 (Ser10) Antibodyis available at Gentaur for Next week Delivery. Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of...

Anti-Notch 1 (Cleaved-Val1744) Antibodyis available at Gentaur for Next week Delivery. Description: Notch proteins are transmembrane receptor that regluate cell fate decisions. Four Notch homologs have been identified in mammals namely Notch 1, Notch 2,...

Anti-ROR2 Antibodyis available at Gentaur for Next week Delivery. Description: Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development...

Anti-TGF-β1 Antibodyis available at Gentaur for Next week Delivery. Description: Transforming growth factor-betas (TGF-βs) mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGF-Beta...

Anti-Angiopoietin-2 Antibodyis available at Gentaur for Next week Delivery. Description: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1...

Anti-phospho-Akt (Ser473) Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery. Description: The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 and Akt 3, which exhibit...

Anti-Akt1 Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery. Description: The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 and Akt 3, which exhibit sequence...

Phospho-LCK (Tyr394) Monoclonal Antibodyis available at Gentaur for Next week Delivery. Description: Lck is a membrane associated tyrosine protein kinases. The Lck gene has been shown to undergo rearrangement and overexpression in some murine lymphomas...

BMPR2 Antibody (NT)is available at Gentaur for Next week Delivery. Description: BMPR2 is a type II serine/threonine receptor kinase that binds to an array of secreted bone morphogenetic proteins (BMPs). BMPs belong to the superfamily of TGF-β ligands...

ROR2 Antibody (CT)is available at Gentaur for Next week Delivery. Description: ROR2 (receptor tyrosine kinase-like orphan receptor 2), also known as neurotrophic tyrosine kinase receptor-related 2 (NTRKR2), is a single pass transmembrane tyrosine-protein...

ROR2 Antibody (NT)is available at Gentaur for Next week Delivery. Description: ROR2 (receptor tyrosine kinase-like orphan receptor 2), also known as neurotrophic tyrosine kinase receptor-related 2 (NTRKR2), is a single pass transmembrane tyrosine-protein...

TDP1 Antibody (Clone AT1F2)is available at Gentaur for Next week Delivery. Description: Tyrosyl-DNA phosphodiesterase (TDP1) is a DNA repair enzyme that catalyzes the hydrolysis of a phophodiester bond between a tyrosine residue and a DNA 3' phosphate...

TDP2 Antibodyis available at Gentaur for Next week Delivery. Description: The TTRAP/TDP2 gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF)...

SPHKAP Antibodyis available at Gentaur for Next week Delivery. Description: Anchoring protein that binds preferentially to the type I regulatory subunit of c-AMP-dependent protein kinase (PKA type I) and targets it to distinct subcellular compartments...

USP8 Antibodyis available at Gentaur for Next week Delivery. Description: Ubiquitinating enzymes (UBEs) catalyze protein ubiquitination, a reversible process countered by deubiquitinating enzyme (DUB) action. Five DUB subfamilies are recognized,...

BMP-11 Antibodyis available at Gentaur for Next week Delivery. Description: BMPs (bone morphogenetic proteins) belong to the TGF-β superfamily of structurally related signaling proteins. As implied by their name, BMPs promote and regulate bone...

Anti-TGF-β1 Polyclonal Antibodyis available at Gentaur for Next week Delivery. Description: TGF-β(transforming growth factor-beta) is a family of multifunctional proteins. TGF-β was originally identified for its ability to induce the growth of normal...

OPG Antibodyis available at Gentaur for Next week Delivery. Description: Human OPG (Osteoprotegerin), also known as OCIF (Osteoclastogenesis inhibitory factor), is a member of the TNF receptor superfamily. It specifically acts on bone tissues and...

IGF-II Antibodyis available at Gentaur for Next week Delivery. Description: IGF-II (Insulin-like Growth Factor-II) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types. Human IGF-II is a 7.5 kDa protein...

Anti-Rat IGF-1 Antibodyis available at Gentaur for Next week Delivery. Description: IGF-I (insulin-like Growth Factor-I) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage...

FGF-18 Antibodyis available at Gentaur for Next week Delivery. Description: The FGFs plays an important role in regulating tissue growth, morphogenesis and tissue repair. FGF-18 is a newly discovered heparin binding growth factor that stimulates the...

FGF-10 Antibodyis available at Gentaur for Next week Delivery. Description: Fibroblast Growth Factor-10 (also called KGF-2) is a heparin binding growth factor that stimulates the proliferation and activation of cells that express FGF receptors. FGF-10 is...

FGF-8 Antibodyis available at Gentaur for Next week Delivery. Description: Fibroblast Growth Factor-8 (FGF-8) is also known as Androgen-induced Growth Factor (AIGF), a heparin binding growth factor, which stimulates the proliferation and activation of...

KGF/FGF-7 Antibodyis available at Gentaur for Next week Delivery. Description: FGF-7, also known as Keratinocyte Growth Factor (KGF), is a potent mitogen for keratinocytes and epithelial cells. The antibody recognizes ~19 kDa of human FGF-7/KGF protein...

FGF-2 Antibodyis available at Gentaur for Next week Delivery. Description: FGF-2 is a basic heparin binding growth factor that stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells...

FGF-1 Antibodyis available at Gentaur for Next week Delivery. Description: FGF-1 is an acidic heparin binding growth factor that stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells. Human...

Phospho-Gab2 (Tyr452) Antibodyis available at Gentaur for Next week Delivery. Description: This gene is a member of the GRB2-associated binding protein (GAB) gene family and is similar to the GAB1 gene. These proteins contain pleckstrin homology (PH)...