Phospho ER-alpha (Ser167) Antibody

Phospho ER-alpha (Ser167) Antibodyis available at Gentaur for Next week Delivery.

Description: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.

Immunogen Sequence:A phospho specific peptide corresponding to residues surrounding Ser167 of human ER-alpha

Target Alternative Name:ESR1; ER; ESR; ESRA; ESTRR; Era; NR3A1; estrogen receptor

Species Reactivities:Human

Tag Line:Affinity purified rabbit polyclonal antibody to detect phosphorylation of ER-alpha at Ser167 in human samples

Formulation:In PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purified

Application:Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting

Positive Control:/

Application And Usages:IF 1:100 - 1:200, IHC 1:50 - 1:100, WB 1:500 - 1:2000

Handling:The antibody solution should be gently mixed before use.