Anti-WT1 recMAb™ Antibody

Anti-WT1 recMAb™ Antibodyis available at Gentaur for Next week Delivery.

Description: This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting patterns, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. A study demonstrated that WT1 mRNA undergoes RNA editing in human and rat and that this process is tissue-restricted and developmentally regulated

Immunogen Sequence:Recombinant full-length human WT1 protein

Target Alternative Name:WT1, AWT1, FWT1, GUD, NPHS4, WAGR, Wilms tumor 1, WT33, WIT-2

Species Reactivities:Rat,Mouse,Human

Tag Line:Recombinant mouse monoclonal antibody to detect WT1 expression in human, mouse and rat samples

Formulation:In 10 mM PBS

Purification: Protein A/G purified

Application:Immunohistochemistry (IHC)

Positive Control:/

Application And Usages:IHC (1-2 µg/ml)

Handling:The antibody solution should be gently mixed before use.