recMAb™ Anti-p53 Antibody

recMAb™ Anti-p53 Antibodyis available at Gentaur for Next week Delivery.

Description: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants

Immunogen Sequence:Recombinant full-length human TP53 protein

Target Alternative Name:P53, BCC7, LFS1, BMFS5, TRP53, TP53

Species Reactivities:Dog,Hamster,Chicken,Does not react with Mouse and Rat,Monkey,Human

Tag Line:Recombinant rabbit monoclonal antibody to detect p53 expression in human, monkey, dog, hamster and chicken samples. The antibody does not react with mouse and rat samples

Formulation:In 10 mM PBS

Purification: Protein A purified

Application:Immunohistochemistry (IHC),Western Blotting

Positive Control:/

Application And Usages:WB (1-2 µg/ml), IHC (1-2 µg/ml)

Handling:The antibody solution should be gently mixed before use.