Anti-MUC1 recMAb™ Antibody

Anti-MUC1 recMAb™ Antibodyis available at Gentaur for Next week Delivery.

Description: This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including the lung, breast stomach, and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.

Immunogen Sequence:Recombinant full-length human MUC1 protein

Target Alternative Name:EMA, MCD, PEM, PUM, KL-6, MAM6, MCKD, PEMT, CD227, H23AG, MCKD1, MUC-1, ADMCKD, ADMCKD1, CA 15-3, MUC-1/X, MUC1/ZD, MUC-1/SEC

Species Reactivities:Human

Tag Line:Recombinant rabbit monoclonal antibody to detect the expression of MUC1 in human samples

Formulation:In 10 mM PBS

Purification: Protein A/G purified

Application:Immunohistochemistry (IHC)

Positive Control:/

Application And Usages:IHC (1-2 µg/ml)

Handling:The antibody solution should be gently mixed before use.