Anti-TIMP2 recMAb™ Antibody

Anti-TIMP2 recMAb™ Antibodyis available at Gentaur for Next week Delivery.

Description: This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

Immunogen Sequence:Synthetic peptide targeting residues around aa 40-70 at the N-terminus of human TIMP2

Target Alternative Name:DDC8, CSC-21K, Metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, Tissue Inhibitor of Metalloproteinase 2

Species Reactivities:Zebrafish,Guinea pig,Bovine,Rat,Rabbit,Mouse,Human

Tag Line:Recombinant mouse monoclonal antibody to detect TIMP2 expression in human, mouse, rat, rabbit, guinea pig, cow and zebrafish samples

Formulation:In 10 mM PBS

Purification: Protein A/G purified

Application:Immunohistochemistry (IHC)

Positive Control:/

Application And Usages:IHC (1-2 µg/ml)

Handling:The antibody solution should be gently mixed before use.