Anti-Smad4 Rabbit Monoclonal Antibody

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SKU:
A1605-50
£215.86
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Description

Anti-Smad4 Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery.

Description: Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF-β and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities throμgh interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.

Immunogen Sequence:A peptide corresponding to the C-terminus of human Smad4

Target Alternative Name:SMAD family member, Mothers against decapentaplegic homolog, MAD homolog, Mothers against DPP homolog, SMAD4

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect Smad4 in human samples.

Formulation:In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Affinity purified

Application:WB, IHC

Positive Control:WB: Jurkat and IMR32 cells lysates, IHC: human breast cancer tissue

Application And Usages:WB: 1:500-1:1000, IHC: 1:1000-1:2000

Handling:The antibody solution should be gently mixed before use.

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Additional Information

Size:
50 µl
Antibody Target:
Smad4
Category:
Signal Transduction
Host:
Rabbit
Antibody Type:
Monoclonal
Isotype:
Rabbit IgG
Accession Number:
Q9BYG6
Gene Id:
4089
Appearance:
Colorless liquid
Form:
Liquid
Storage Condition:
-20 °C
Shipping Condition:
gel pack
Shelf Life:
12 months
Country of Animal Origin:
USA
Country of Manufacture:
USA
Usage:
For Research Use Only! Not to be used in humans.
Western Blot Verified:
Verified
Immunocytochemistry Verified:
Verified
Immunofluorescence Verified:
Not Verified
Immunoprecipitation Verified:
Not Verified
FACS Verified:
Not Verified
ELISA Verified:
Not Verified
ChIP Verified:
Not Verified
Dot Blot Verified:
Not Verified
Flow Cytometry Verified:
Not Verified
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