Anti-ACTA2 Rabbit Monoclonal Antibody

Anti-ACTA2 Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery.

Description: Actins are highly conserved proteins expressed in all eucaryotic cells. Actin filaments form part of the cytoskeleton and play essential roles in regulating cell shape and movement. Six distinct actin isotypes have been identified in mammalian cells. Each is encoded by a separated gene and is expressed in a developmentally regulated and tissue-specific manner, alpha and beta cytoplasmic actins are expressed in a wide variety of cells; whereas, expression of alpha skeletal, alpha cardiac, alpha vascular, and gamma enteric actins are more restricted to specialized muscle cell type. Smooth muscle alpha actin is of further interest because it is one of a few genes whose expression is relatively restricted to vascular smooth muscle cells. Furthermore, expression of smooth muscle alpha actin is regulated by hormones, cell proliferation, and altered by pathological conditions including oncogenic transformation and atherosclerosis.

Immunogen Sequence:A synthetic peptide corresponding to the N-terminus of human alpha smooth muscle Actin

Target Alternative Name:alpha smooth muscle Actin Alpha-actin-2, Cell growth-inhibiting gene 46 protein

Species Reactivities:Human and mouse

Tag Line:Rabbit monoclonal antibody to detect ACTA2 in human and mouse samples.

Formulation:In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Affinity purified using protein A

Application:IHC, WB

Positive Control:WB: heart tissue lysate, IHC: kidney and heart tissue sections

Application And Usages:IHC: 1:1000 -1:2500 dilution; WB: 1:1000 - 1:2000 dilution

Handling:The antibody solution should be gently mixed before use.