TWEAK, human recombinant

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SKU:
4360-1000
$719.07
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Description

TWEAK, human recombinant is available at Gentaur for Next week delivery.

An apoptosis inducer

Biomolecule/Target: TWEAK

Alternates names: APO3L, DR3LG, TWEAK, TNFSF13

Synonyms: APO3L, DR3LG, TWEAK, TNFSF13

Background Information: Human TWEAK is a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. TWEAK, like many other members of the TNF family, is able to induce interleukin-8 synthesis in a number of cell lines. The recombinant human TWEAK is a 17.0 kDa protein, comprising the TNF-like extraCellular domain of TWEAK.

Reconstitution Instructions: Reconstitute in 10 mM Sodium Phosphate (pH 7.5) to a concentration of 1 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

NCBI Gene Symbol: TNFSF12

Gene ID: 8742

NCBI Accession: O43508

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Additional Information

Size:
1 mg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The ED₅₀ as determined by the dose-dependent stimulation of IL-8 production by human PBMC is less than 10 ng/ml.
Results:
<10 ng/ml.
Molecular Weight:
17.0 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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