TDRD12-BD2 (908-999 aa) (His-Tagged), human recombinant

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SKU:
7254-20
€185
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Description

TDRD12-BD2 (908-999 aa) (His-Tagged), human recombinant is available at Gentaur for Next week delivery.

Involved in RISC complex and interaction with AEG-1 oncogene

Biomolecule/Target: TDRD12

Alternates names: ECAT8

Synonyms: ECAT8

Background Information: Tudor domains are small protein structural motifs of about ~50 amino acids related to the “royal family” of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The tudor domains recognize symmetric methylated arginine or methylated lysine residues. Tudor domain proteins act as an oncogene and play a very important role in HCC and colon cancer. TDRD is also involved in RISC complex and interacts with AEG-1 oncogene. The tudor domain can bind to methylated arginine protein and promote tumor angiogenesis in human hepatocellular carcinoma, etc. The recombinant protein includes TDRD12 (domain 908-999aa) with N-terminal His-tag.

Reconstitution Instructions: N/A

NCBI Gene Symbol: TDRD12

Gene ID: 91646

NCBI Accession: Q587J7

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Additional Information

Size:
20 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
N/A
Biological activity:
N/A
Results:
N/A
Molecular Weight:
13 kDa
Storage Temperature:
-80°C
Shelf Life:
12 months
Concentration:
2 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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