Description
TDRD12-BD2 (908-999 aa) (His-Tagged), human recombinant is available at Gentaur for Next week delivery.
Involved in RISC complex and interaction with AEG-1 oncogene
Biomolecule/Target: TDRD12
Alternates names: ECAT8
Synonyms: ECAT8
Background Information: Tudor domains are small protein structural motifs of about ~50 amino acids related to the “royal family” of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The tudor domains recognize symmetric methylated arginine or methylated lysine residues. Tudor domain proteins act as an oncogene and play a very important role in HCC and colon cancer. TDRD is also involved in RISC complex and interacts with AEG-1 oncogene. The tudor domain can bind to methylated arginine protein and promote tumor angiogenesis in human hepatocellular carcinoma, etc. The recombinant protein includes TDRD12 (domain 908-999aa) with N-terminal His-tag.
Reconstitution Instructions: N/A
NCBI Gene Symbol: TDRD12
Gene ID: 91646
NCBI Accession: Q587J7
Additional Information
Size: |
20 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥98% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
13 kDa |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
2 mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |