Description
Tau-441, Human Recombinant is available at Gentaur for Next week delivery.
Microtubule-associated protein that promotes microtubule assembly and stability.
Biomolecule/Target: MAPT
Alternates names: MAPTL, MTBT1, TAU, Neurofibrillary tangle protein, Paired helical filament-tau
Synonyms: MAPTL, MTBT1, TAU, Neurofibrillary tangle protein, Paired helical filament-tau
Background Information: Tau is a microtubule-associated protein involved in Alzheimer’s and Parkinson’s disease. It promotes microtubule assembly and stability, and might participate in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Reconstitution Instructions: Reconstitute to 4 mg/mL in sterile water.
NCBI Gene Symbol: MAPT
Gene ID: 4137
NCBI Accession: P10636
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E.coli |
Purity by SDS-PAGE: |
> 90% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
48 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |