Human Tau-352

Human Tau-352 is available at Gentaur for Next week delivery.

A tau isoform

Biomolecule/Target:

Alternates names: Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau; MAPTL; MTBT1; Tau 0N3R; tau isoform 4; ht23; 3RS tau

Synonyms: Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau; MAPTL; MTBT1; Tau 0N3R; tau isoform 4; ht23; 3RS tau

Background Information: Tau is a neuronal microtubule-associated protein. It stabilizes microtubules in axons. Tau protein become hyperphosphorylated and forms insoluble aggregates called neurofibrillary tangles in Alzheimer's disease. The accumulation of abnormal tau aggregates causes cytoxicity, which is described as a gain-of-toxic function model. Tau gene undergoes alternative splicing, giving rise to six different isoforms. Tau-352 isoform lacks exons 2, 3 and 10.

Reconstitution Instructions:

NCBI Gene Symbol:

Gene ID:

NCBI Accession: P10636, NP_058525