S-adenosylmethionine synthetase (AdoMetS), Active, E. coli Recombinant

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SKU:
P1211-50
€185
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Description

S-adenosylmethionine synthetase (AdoMetS), Active, E. coli Recombinant is available at Gentaur for Next week delivery.

Catalyzes the formation of AdoMet from methionine and ATP

Biomolecule/Target: S-adenosylmethionine synthase

Alternates names: Methionine adenosyltransferase, AdoMet synthetase, MAT

Synonyms: Methionine adenosyltransferase, AdoMet synthetase, MAT

Background Information: S-Adenosylmethionine synthase, (AdoMetS), (E.C. 2.5.1.6) catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. BioVision’s active AdoMetS is suitable for functional assays, high-throughput screening and preclinical studies in drug discovery.

Reconstitution Instructions: N/A

NCBI Gene Symbol: metK

Gene ID: 945389

NCBI Accession: P0A817

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Additional Information

Size:
50 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E.coli
Purity by SDS-PAGE:
> 90%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
N/A
Endotoxin Level:
N/A
Activity (Specifications/test method):
Measured by its ability to converts 1 μmole of L-methionine and ATP to S-adenosyl-L-methionine (AdoMet), inorganic phosphate (Pi), and pyrophosphate (PPi) at 37ºC and pH 7
Biological activity:
Specific activity ≥50 mU/mg.
Results:
≥10 U/mg
Molecular Weight:
43 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
3.6 mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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