ProNGF, human recombinant

ProNGF, human recombinant is available at Gentaur for Next week delivery.

Neuronal apoptosis inducer

Biomolecule/Target: ProNGF

Alternates names: Beta-nerve growth factor (Beta-NGF)

Synonyms: N/A

Background Information: The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystine knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.

Reconstitution Instructions: Dissolve in 1x PBS (It is not recommended to reconstitute to a final concentration less than 100 μg/ml.). This can further be diluted to other aqueous buffers.

NCBI Gene Symbol: NGF

Gene ID: 4803

NCBI Accession: P01138