Description
ProNGF, human recombinant is available at Gentaur for Next week delivery.
Neuronal apoptosis inducer
Biomolecule/Target: ProNGF
Alternates names: Beta-nerve growth factor (Beta-NGF)
Synonyms: N/A
Background Information: The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystine knot motif consisting of three cystine bridges, whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
Reconstitution Instructions: Dissolve in 1x PBS (It is not recommended to reconstitute to a final concentration less than 100 μg/ml.). This can further be diluted to other aqueous buffers.
NCBI Gene Symbol: NGF
Gene ID: 4803
NCBI Accession: P01138
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥95% |
Assay: |
SDS-PAGE |
Purity: |
≥95% |
Assay 2: |
HPLC |
Endotoxin Level: |
<0.1 ng/μg (1 IEU/μg) |
Activity (Specifications/test method): |
N/A |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
~25 kDA |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |