PKCepsilon, Active

PKCepsilon, Active is available at Gentaur for Next week delivery.

Phosphorylate a wide variety of protein targets

Biomolecule/Target:

Alternates names: PKC, protein kinase C, epsilon

Synonyms: PKC, protein kinase C, epsilon

Background Information: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. Protein kinase C epsilon (PRKCE), one of the PKC family members, has been shown to be involved in many different cellular functions, such as neuron channel activation (1), apoptosis (2), cardioprotection from ischemia (3, 4), heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior (5).

Reconstitution Instructions: N/A

NCBI Gene Symbol: PRKCE

Gene ID: 5581

NCBI Accession: Q02156