PDGFR beta, Active

PDGFR beta, Active is available at Gentaur for Next week delivery.

Important factors regulating cell proliferation, cellular differentiation, cell growth and development

Biomolecule/Target:

Alternates names: PDGR. platelet-derived growth factor receptor, beta polypeptide

Synonyms: PDGR. platelet-derived growth factor receptor, beta polypeptide

Background Information: PDGFRb (platelet-derived growth factor receptor b) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. PDGFRb deficient mice are hemorrhagic, severely anemic and exhibit a defect in kidney glomeruli function (1). However, absence of PDGFRb has no impact on major blood vessels and the heart. PDGFRb expression and activity is elevated in several cancers and inhibition of PDGFRb activity blocks progression of renal carcinoma in an animal model (2).

Reconstitution Instructions: N/A

NCBI Gene Symbol: PDGFRB

Gene ID: 5159

NCBI Accession: NM_002609.