PDGFR beta, Active

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SKU:
7770-5
$183
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Description

PDGFR beta, Active is available at Gentaur for Next week delivery.

Important factors regulating cell proliferation, cellular differentiation, cell growth and development

Biomolecule/Target:

Alternates names: PDGR. platelet-derived growth factor receptor, beta polypeptide

Synonyms: PDGR. platelet-derived growth factor receptor, beta polypeptide

Background Information: PDGFRb (platelet-derived growth factor receptor b) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. PDGFRb deficient mice are hemorrhagic, severely anemic and exhibit a defect in kidney glomeruli function (1). However, absence of PDGFRb has no impact on major blood vessels and the heart. PDGFRb expression and activity is elevated in several cancers and inhibition of PDGFRb activity blocks progression of renal carcinoma in an animal model (2).

Reconstitution Instructions: N/A

NCBI Gene Symbol: PDGFRB

Gene ID: 5159

NCBI Accession: NM_002609.

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Additional Information

Size:
5 μg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Recombinant:
Yes
Source:
Baculovirus (Sf9 insect cells)
Purity by SDS-PAGE:
≥90%
Assay:
SDS-PAGE
Purity:
N/A
Assay 2:
HPLC
Endotoxin Level:
N/A
Activity (Specifications/test method):
The specific activity of PDGFRb was determined to be 20 nmol /min/mg as per activity assay protocol.
Biological activity:
N/A
Results:
N/A
Molecular Weight:
96.0 kDa
Storage Temperature:
-80°C
Shelf Life:
12 months
Concentration:
0.1mg/ml
Appearance:
Liquid
Handling:
Centrifuge the vial prior to opening.
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