Description
PDGFR beta, Active is available at Gentaur for Next week delivery.
Important factors regulating cell proliferation, cellular differentiation, cell growth and development
Biomolecule/Target:
Alternates names: PDGR. platelet-derived growth factor receptor, beta polypeptide
Synonyms: PDGR. platelet-derived growth factor receptor, beta polypeptide
Background Information: PDGFRb (platelet-derived growth factor receptor b) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. PDGFRb deficient mice are hemorrhagic, severely anemic and exhibit a defect in kidney glomeruli function (1). However, absence of PDGFRb has no impact on major blood vessels and the heart. PDGFRb expression and activity is elevated in several cancers and inhibition of PDGFRb activity blocks progression of renal carcinoma in an animal model (2).
Reconstitution Instructions: N/A
NCBI Gene Symbol: PDGFRB
Gene ID: 5159
NCBI Accession: NM_002609.
Additional Information
Size: |
5 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Recombinant: |
Yes |
Source: |
Baculovirus (Sf9 insect cells) |
Purity by SDS-PAGE: |
≥90% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
HPLC |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
The specific activity of PDGFRb was determined to be 20 nmol /min/mg as per activity assay protocol. |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
96.0 kDa |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
0.1mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |