Description
PDGF-BB, human recombinant is available at Gentaur for Next week delivery.
A growth factor that regulates cell growth and division
Biomolecule/Target: PDGF-BB
Alternates names: Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, SIS, SSV, PDGF2, c-sis, FLJ12858, PDGF-BB, PDGF B-chain, Platelet-derived growth factor β polypeptide, Becaplermin.
Synonyms: Glioma-derived growth factor, GDGF, Osteosarcoma-derived Growth Factor, ODGF, SIS, SSV, PDGF2, c-sis, FLJ12858, PDGF-BB, PDGF B-chain, Platelet-derived growth factor β polypeptide, Becaplermin.
Background Information: Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF, which is composed of a dimer of two chains termed the A chain and B chain, can be present as AA or BB homodimers or as an AB heterodimer. Human PDGF-BB is a 24.3 kDa B chain homodimer protein formed by subunits of 109 amino acid residues.
Reconstitution Instructions: Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
NCBI Gene Symbol: PDGFB
Gene ID: 5155
NCBI Accession: P01127
Additional Information
Size: |
50 μg |
Adwords: |
yes |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥98% |
Assay: |
SDS-PAGE |
Purity: |
≥98% |
Assay 2: |
HPLC |
Endotoxin Level: |
<0.1 ng/μg |
Activity (Specifications/test method): |
N/A |
Biological activity: |
The ED₅₀ as determined by the dose-dependent stimulation of thimidine uptake by BALB/c 3T3 cells is < 1 ng/ml, corresponding to a specific activity of > 1 x 10⁶ units/mg. |
Results: |
< 1 ng/ml |
Molecular Weight: |
24.3 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |