Oncostatin M, human recombinant

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SKU:
4466-1000
£135.37
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Description

Oncostatin M, human recombinant is available at Gentaur for Next week delivery.

A pleiotropic cytokine important in liver development, haematopoeisis, inflammation and possibly CNS development

Biomolecule/Target: Oncostatin M

Alternates names: OSM, MGC20461, Oncostatin M.

Synonyms: OSM, MGC20461, Oncostatin M.

Background Information: Oncostatin M (OSM) is an important growth regulating cytokine that affects, variably, a number of tumor and normal cells. Oncostatin M exerts inhibitory effects on the growth of A375 melanoma and other cellos, but augments the growth of normal fibroblasts, AIDs-related Kaposi sarcoma cells, and certain other cells. Recombinant Human Oncostatin M is a 26 kDa protein containing 227 amino acid residues.

Reconstitution Instructions: Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

NCBI Gene Symbol: ONCM

Gene ID: 5008

NCBI Accession: P13725

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Additional Information

Size:
1 mg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E. coli
Purity by SDS-PAGE:
≥98%
Assay:
SDS-PAGE
Purity:
≥98%
Assay 2:
HPLC
Endotoxin Level:
<0.1 ng/μg
Activity (Specifications/test method):
N/A
Biological activity:
The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is <2 ng/ml, corresponding to a specific activity of >5 x 10⁵ units/mg.
Results:
<2 ng/ml
Molecular Weight:
26.0 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized protein
Handling:
Centrifuge the vial prior to opening.
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