Description
Oncostatin M, human recombinant is available at Gentaur for Next week delivery.
A pleiotropic cytokine important in liver development, haematopoeisis, inflammation and possibly CNS development
Biomolecule/Target: Oncostatin M
Alternates names: OSM, MGC20461, Oncostatin M.
Synonyms: OSM, MGC20461, Oncostatin M.
Background Information: Oncostatin M (OSM) is an important growth regulating cytokine that affects, variably, a number of tumor and normal cells. Oncostatin M exerts inhibitory effects on the growth of A375 melanoma and other cellos, but augments the growth of normal fibroblasts, AIDs-related Kaposi sarcoma cells, and certain other cells. Recombinant Human Oncostatin M is a 26 kDa protein containing 227 amino acid residues.
Reconstitution Instructions: Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.
NCBI Gene Symbol: ONCM
Gene ID: 5008
NCBI Accession: P13725
Additional Information
Size: |
1 mg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥98% |
Assay: |
SDS-PAGE |
Purity: |
≥98% |
Assay 2: |
HPLC |
Endotoxin Level: |
<0.1 ng/μg |
Activity (Specifications/test method): |
N/A |
Biological activity: |
The ED₅₀ as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is <2 ng/ml, corresponding to a specific activity of >5 x 10⁵ units/mg. |
Results: |
<2 ng/ml |
Molecular Weight: |
26.0 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |