Description
MRCK beta, Active is available at Gentaur for Next week delivery.
Involved in the regulation of cytoskeleton reorganization, cell migration, wound healing and invasion
Biomolecule/Target:
Alternates names: MRCK, CDC42 binding protein kinase beta (DMPK-like), DMPK-like beta, Myotonic dystrophy kinase-related CDC42-binding kinase beta
Synonyms: MRCK, CDC42 binding protein kinase beta (DMPK-like)
Background Information: Myotonic Dystrophy Kinase-Related cdc42-binding kinase β (MRCKb) belongs to the DMPK subfamily (1). The myotonic dystrophy kinase-related kinases and myotonic dystrophy kinase-related Cdc42 binding kinase (MRCK) are effectors of RhoA and Cdc42, respectively, where they are involved in actin cytoskeletal reorganization and neurite outgrowth (2). Effects of the repeat expansion on the DMPK gene may be responsible for muscle and heart features of Myotonic Dystrophy.
Reconstitution Instructions: N/A
NCBI Gene Symbol: CDC42
Gene ID: 9578
NCBI Accession: NM_006035.
Additional Information
Size: |
5 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Recombinant: |
Yes |
Source: |
Baculovirus (Sf9 insect cells) |
Purity by SDS-PAGE: |
≥90% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
HPLC |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
The specific activity of MRCKB was determined to be 120 nmol /min/mg as per activity assay protocol. |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
73.0 kDa |
Storage Temperature: |
-80°C |
Shelf Life: |
12 months |
Concentration: |
0.1mg/ml |
Appearance: |
Liquid |
Handling: |
Centrifuge the vial prior to opening. |