Description
MIA-2, human recombinant is available at Gentaur for Next week delivery.
Potential role in the pathophysiology of liver disease
Biomolecule/Target:
Alternates names: Melanoma inhibitory activity protein 2, Melanoma inhibitory activity protein 2
Synonyms: Melanoma inhibitory activity protein 2
Background Information: MIA2 performs as a tumour suppressor in hepatocellular carcinoma. MIA2 is a novel acute phase protein which its expression is found in the liver and reacts to liver damage in chronic liver diseases and is considerably higher in severe fibrosis patients . MIA2 is induced by IL6, TGF-b and conditioned medium from activated hepatic stellate cells. MIA2 is is mainly expressed in hepatocytes. MIA2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain consisting of 101 amino having a total molecular mass of 11.5 kDa. The MIA2 is purified by proprietary chromatographic techniques.
Reconstitution Instructions: Reconstitute in sterile H₂O at >100 µg/ml. Reconstituted MIA2 should be stored in working aliquots at -20°C.
NCBI Gene Symbol: MIA2
Gene ID: 117153
NCBI Accession: Q96PC5
Additional Information
Size: |
20 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Human |
Recombinant: |
Yes |
Source: |
E. coli |
Purity by SDS-PAGE: |
≥97% |
Assay: |
SDS-PAGE |
Purity: |
≥97% |
Assay 2: |
HPLC |
Endotoxin Level: |
N/A |
Activity (Specifications/test method): |
N/A |
Biological activity: |
N/A |
Results: |
N/A |
Molecular Weight: |
11.5 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized protein |
Handling: |
Centrifuge the vial prior to opening. |