LIGHT, Murine Recombinant

LIGHT, Murine Recombinant is available at Gentaur for Next week delivery.

Apoptosis inducer

Biomolecule/Target: LIGHT

Alternates names: TNFSF14, HVEM-L, Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, Herpesvirus entry mediator ligand, CD258, LIGHT

Synonyms: TNFSF14, HVEM-L, Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, Herpesvirus entry mediator ligand, CD258, LIGHT

Background Information: LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFκB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant murine LIGHT is a 20.1 kDa protein containing 183 amino acid residues.

Reconstitution Instructions: DI water (~1 mg/ml)

NCBI Gene Symbol:

Gene ID:

NCBI Accession: Q9QYH9