LAG-1 (CCL4L1), Human Recombinant

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SKU:
P1290-5
£135.37
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Description

LAG-1 (CCL4L1), Human Recombinant is available at Gentaur for Next week delivery.

LAG-1 is CC chemokine that signals through the CCR5 receptor

Biomolecule/Target: LAG-1 (CCL4L1)

Alternates names: Lymphocyte Activation Gene-1, CCL4L1, ACT-2, T-cell activiation-2, HC21, C-C motif chemokine 4-like, Lymphocyte activation gene 1 protein, LAG-1, Macrophage inflammatory protein 1-beta, MIP-1-beta, Monocyte adherence-induced protein 5-alpha, Small-inducible cytokine A4-like

Synonyms: Lymphocyte Activation Gene-1, CCL4L1, ACT-2, T-cell activiation-2, HC21, C-C motif chemokine 4-like, Lymphocyte activation gene 1 protein, LAG-1, Macrophage inflammatory protein 1-beta, MIP-1-beta, Monocyte adherence-induced protein 5-alpha, Small-inducible cytokine A4-like

Background Information: LAG-1 is CC chemokine receptor (beta chemokine receptors) that signals through the CCR5 receptor. LAG-1 is identical to MIP-1β (ACT II isotype) except for two amino acid substitutions; arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV suppressive factor. Recombinant human LAG-1 is a 7.7 kDa protein containing 69 amino acid residues.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

NCBI Gene Symbol:

Gene ID:

NCBI Accession: Q8NHW4

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Additional Information

Size:
5 µg
Country of Manufacturing Origin:
USA
Country of Animal Origin:
USA
Gene Source:
Human
Recombinant:
Yes
Source:
E.coli
Purity by SDS-PAGE:
≥ 98%
Assay:
SDS-PAGE
Endotoxin Level:
<0.1 EU/μg
Biological activity:
Determined by its ability to chemoattract CCR5 transfected cells using a concentration of 0.1-10.0 ng/ml
Molecular Weight:
7.7 kDa
Storage Temperature:
-20°C
Shelf Life:
12 months
Concentration:
N/A
Appearance:
Lyophilized
Handling:
Centrifuge the vial prior to opening.
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