BioVision Proteins
Human CellExp™ LAG-3 / CD223, Cynomolgus Recombinant
- SKU:
- P1179-50
Description
Human CellExp™ LAG-3 / CD223, Cynomolgus Recombinant is available at Gentaur for Next week delivery.
A protein involved in lymphocyte activation
Biomolecule/Target: LAG4
Alternates names: LAG3, CD223, FDC
Synonyms: LAG3, CD223, FDC
Background Information: Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.
Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.
NCBI Gene Symbol: LAG-3
Gene ID: 102122272
NCBI Accession: XP_005570011.1
Additional Information
Size: |
50 μg |
Country of Manufacturing Origin: |
USA |
Country of Animal Origin: |
USA |
Gene Source: |
Cynomolgus |
Recombinant: |
Yes |
Source: |
HEK293 cells |
Purity by SDS-PAGE: |
> 85% |
Assay: |
SDS-PAGE |
Purity: |
N/A |
Assay 2: |
N/A |
Endotoxin Level: |
< 1.0 EU per/μg |
Activity (Specifications/test method): |
Measured by its binding ability in a functional ELISA. |
Biological activity: |
Immobilized Cynomolgus LAG-3, mouse IgG2a Fc tag at 2 μg/mL (100 μl/well) can bind Anti-LAG3 MAb,Human IgG1 with a linear range of 3-20 ng/ml. |
Results: |
N/A |
Molecular Weight: |
73.7 kDa |
Storage Temperature: |
-20°C |
Shelf Life: |
12 months |
Concentration: |
N/A |
Appearance: |
Lyophilized |
Handling: |
Centrifuge the vial prior to opening. |